Nursing, Allied Health & Locums
Local, Travel & Per Diem
Adventure Awaits -- Connecting Nurses, Allied Health, and Locums Professionals
with Opportunities Across the East Coast—and Beyond.
Your Next Adventure Starts Here
Browse jobs and apply now.
Pack Your Bag - Your Next Adventure Awaits!
At Plexsum Staffing Solutions, we specialize in connecting talented nurses, allied health professionals, and locum tenens providers with rewarding assignments across the country. Headquartered in Central Pennsylvania and growing fast, we’re proud to serve healthcare facilities in multiple states—and we’re just getting started.
Whether you’re drawn to the energy of Philadelphia, the charm of Pittsburgh, the warmth of Palm Beach, or the sun-soaked days in Phoenix, Plexsum has opportunities where you want to live and work.
Let's get started.
Workforce Solutions: Your Partner in Healthcare Staffing
At Plexsum Staffing Solutions, we deliver qualified, compassionate healthcare professionals who make a measurable impact on patient care. Whether you’re filling gaps or building a reliable care team, our flexible staffing solutions are designed to meet your needs. We offer:
- Travel Assignments
- Local Contracts
- Per Diem Coverage
People Are Raving About Plexsum...
I started working with Plexsum because of Brandon P. He’s honest, straightforward, and really gets what it’s like on our side. He made the whole process smooth and fast. Plexsum’s team is helpful and efficient. If you’re ready to move, they’ll get you working!
Oheneba, RRT
Transitioning to Agency Gave Me More Control!
I have spent the majority of my healthcare career working in a structured hospital environment. The transition to agency nursing left me slightly anxious with stability concerns. Working with Plexsum has given me confidence through their continual personal support and clear communication. With Plexsum I feel appreciated as an RN entrepreneur and enjoy the control I have over my career.
Dave, Agency RN
Plexsum is truly a great company to work for. Everyone treats you like family and wants what’s best for you. All of the recruiters I have worked with are phenomenal.
Seth, Surgical Technician
“Working with this ED RN was an absolute pleasure. From day one, she hit the ground running—confident, competent, and ready to contribute. She quickly adapted to our fast-paced environment and integrated seamlessly with our team. Not only was she consistently dependable and always on time, but she also stood out for the exceptional care she provided to our patients. Her compassion didn’t go unnoticed—several patients nominated her for DAISY Awards, which speaks volumes about the impact she made. We’d welcome her back any time.”
Jason, Unit Director
Extremely Helpful!
I have been with Plexsum Staffing Solutions since early into their inception into agency nursing. Everyone at Plexsum has always been extremely helpful with any concerns and problems I have encountered. For anyone considering a career in agency nursing or any facilities considering hiring agency nurses, I strongly recommend Plexsum Staffing Solutions as your highly skilled, professional choice.
Denny, RN
As a nurse leader and former hospital CNO, I was fortunate to have a relationship with Plexsum and to be supported by high quality Plexsum nurses during very challenging times in healthcare. I am so excited to have had the opportunity before retiring to work with the amazing individuals that make up the Plexsum internal team!
Tracy W. – Former CNO, Retired Healthcare Professional
Great Experiences and Love My Benefits!
Working for Plexsum has been a great experience for me. I have been given the opportunity to be placed at different sites to utilize my skills as a nurse with help from the hardworking staff of Plexsum. The pay is great, and I love getting paid weekly. The benefits Plexsum offers are very competitive and glad they offer a 401(k). I am so glad I chose to become a travel nurse with Plexsum and have been for almost 4 years. My future looks bright with Plexsum and glad I made this career shift.
Michael, LPN
First Experience Is Great!
Plexsum Staffing has been a godsend! I love this agency. This is my first experience with a travel agency, and I’m so glad I chose Plexsum. Doug has always made sure everything is alright and checks on how I’m doing in general. I’m dealt with as a human being and not just another number. Great company!
Erica, CNA
Plexsum News
Insights, events, and advice for healthcare providers and employers.

1099 or Not 1099? What Nurses & Allied Health Professionals Need to Know About the Risks of Being an Independent Contractor
By Darla Hardy, DNP, RN, Vice President Client Relations & Business Development In today’s evolving healthcare landscape, nurses and allied health professionals are increasingly exploring

Thorough Credentialing Still Matters: A Look at App-Based vs. Traditional Healthcare Staffing
By Darla Hardy, DNP, RN, Vice President Client Relations & Business Development In the evolving landscape of healthcare staffing, convenience and speed have become major

The Real Cost of Nurse Turnover: What Hospitals Need to Know in 2025
By Darla Hardy DNP, RN, Vice President Client Relations & Business Development At Plexsum Staffing Solutions, we work side-by-side with healthcare leaders every day who